Yusran Adhitya Kurniawan’s Blog

Archive for May 24th, 2010

Terrible Effects of Electrocuted

by on May.24, 2010, under Information Technology

electricityShocking by electricity can be a scary thing for anyone, because if the high-voltage or prolonged can cause death. Any injury suffered by the people who electrocuted?

Electricity is one of the requirements for helping a variety of activities. But if someone is not careful in its use, it is actually useful things could endanger yourself and those around him.

As quoted from HowStuffWorks, human body is a conductor (electrically conductive) that is very good, because about 70 percent of the human body consists of water.

This makes it very easy flow of electricity through the human body in seconds. The higher the electric current and long accepted by the body, the more serious injuries caused.

Regardless of the electricity received by the body still cause shock or vibration. But this stress can sometimes be felt by someone but there is also not felt by the body.

Minimal small electrical shocks can cause a person experience headaches, fatigue or muscle spasms, unconsciousness, and shortness of breath while temporary.

But if it lasts longer or in higher voltage can cause burns, vision loss, brain damage, heart attacks, stop breathing and death.

If someone in shock for a moment, then only will cause pain. But if the voltage is high enough can also cause fatal, although only a few seconds. For example if the flow reaches 100 mA, the possibility can cause death in just over two seconds.

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D’Genetic of Technology Moving From Lab to Medical Practices

by on May.24, 2010, under Information Technology

technology2In January, practicing doctors and doctors-to-be entered a new class at the Medical College of Wisconsin with a futuristic name, “Translational Genetics.” The idea was simpler than it sounded: We are fast approaching the time when doctors will use our genetic profiles to treat us.

One of the students was Kevin Regner, a practicing kidney doctor at Froedtert Hospital, who had been hearing for years, “Personalized medicine is just around the corner.” Doctors will tailor treatments to each patient's genes and the risks they reveal. It will all be routine.

Regner had doubts. Sequencing of the first human genome in 2003 took more than a decade and cost about $600 million – an effort too herculean to assume doctors would repeat it with patients and insurance companies would foot the bill anytime soon.

But Regner was in for a surprise. As he and his classmates listened, Howard Jacob, head of the college's Human and Molecular Genetics Center, described what has happened since completion of the genome project. He showed two photos: a machine that helped sequence the first human genome in 2003, and then a machine the Medical College has today. The new model does the work of 200 of the old ones; it can sequence a human genome in a few months for several hundred thousand dollars.

And the Medical College has already ordered next-generation sequencers. Within less than a decade, a complete genetic blueprint could be attainable in 15 minutes for as little as $100.

Moreover, in a case that suggests the technology is beginning the journey from research to medical practice, Jacob described how he and his colleagues used a targeted version of gene-sequencing to diagnose and treat an apparently new disease in a young boy at Children's Hospital of Wisconsin.

In the audience, Regner had a moment of recognition. “It's likely we'll see this kind of personalized medicine in my lifetime,” he said, “and in the course of my medical practice.”

Med schools join in

Medical schools are coming to this recognition as well – albeit too slowly for some. Already, companies such as 23andMe and Navigenics are selling personal genetics tests, offering consumers the chance to learn their risks for dozens of diseases. This month pharmacy giant Walgreens announced it would sell a personal genetic test in thousands of stores across the country, though the company put the plans on hold after federal regulators said the tests had not been approved.

“More and more patients are going to be walking into their doctor's office with genes sequenced,” said George Church, a genetics professor at Harvard Medical School and one of the pioneers of gene sequencing. “Very few doctors even know where to refer them.”

In years to come, however, some say gene-sequencing and analysis could take a place in the medical tool kit alongside such fundamentals as anatomy and family history.

Eric J. Topol, director of the Scripps Translational Science Institute in La Jolla, Calif., said there are now genetic tests that determine how patients will respond to specific medications such as Plavix, a widely used blood clot prevention drug. Some tests even reveal appropriate dosages. Yet when researchers surveyed more than 10,000 physicians, just 10% said they had the necessary information and training to use the tests, according to a report in October by the American Medical Association and Medco.

“The resistance to change in medicine, which is profound,” Topol said, “is something that is part lack of education.”

Some of the country's leading medical schools and institutions have launched programs to close the education gap.

• At Harvard Medical School and Beth Israel Deaconess Medical Center, doctors started a first-in-the-nation program last fall to teach pathology residents about genomics and to train them to interpret genetic data. Residents all had the option of using a Navigenics test to search their own genes for common mutations. Twelve out of 17 volunteered for the testing and discussed the results with genetics counselors, said Mark Boguski, an associate professor at Harvard Medical School who works in Beth Israel's pathology department.

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